Hormone-free‡ EQUELLE with naturally derived S-equol helps reduce hot flashes and muscle aches associated with menopause.†
Frequently Asked Questions
About EQUELLE & How to Use
The ingredients in EQUELLE are: Fermented Soy Germ (S-equol source), Cellulose Gel, Calcium Phosphate, Stearic Acid, Sorbitol, Silicon Dioxide, Sodium Silicate, Croscarmellose Sodium, Organic Coating (Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum).
The active ingredient in EQUELLE is S-equol, a naturally derived compound of the soy isoflavone daidzein that is produced through the fermentation of soy germ. This molecule naturally occurs in the gut of some women after eating soy, and may result in fewer hot flashes† for menopausal women. It is structurally similar to estrogen, and mimics some, but not all, estrogenic activities.
The inactive ingredients, necessary for the manufacturing and coating of EQUELLE tablets, include: Cellulose Gel, Calcium Phosphate, Stearic Acid, Sorbitol, Silicon Dioxide, Sodium Silicate, Croscarmellose Sodium, Organic Coating (Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum).
Isoflavones are plant-based compounds present in very small amounts in many foods, but found most abundantly in soybeans. Isoflavones are thought to have antioxidant properties with the potential to positively affect health. Soy isoflavones are sometimes used as a supplement for the management of menopausal symptoms. The three main isoflavones naturally occurring in soybeans are genistein, daidzein and glycitein.Although EQUELLE contains trace amounts of soy isoflavones, the main ingredient in EQUELLE is S-equol, a naturally derived compound of the soy isoflavone daidzein.
S-equol, EQUELLE’s active ingredient, is structurally similar to estrogen and can mimic some of its actions in the body, helping to alleviate some symptoms off decreasing estrogen levels during menopause.†
Yes. EQUELLE's active ingredient, S-equol, is derived from soy germ, which is rich in soy isoflavones. Soy isoflavones share a similar structure to human estrogen, which classifies them a phytoestrogen or plant-based estrogen.EQUELLE is a supplement that contains a standardized amount of its active ingredient, S-equol, in every tablet. Many other supplements for menopause are herbal supplements. The growing conditions and potency of herbs (such as black cohosh or evening primrose oil) are varied and inconsistent, making them hard to rely on for effective, consistent results.
The active ingredient in EQUELLE, S-equol, is derived naturally through a patented process in which soy germ is fermented. Fermentation is a natural process that is commonly used to make everyday foods & beverages such as beer, wine, cheese and yogurt.
Fermented soy germ is when soy germ undergoes a process with bacteria that allows for production of key compounds. EQUELLE's active ingredient, S-equol, is produced through a patented process in which soy germ is fermented. The type of bacteria used in this process is commonly found in diet through foods that undergo fermentation processes such as cheese. It may also be found in the human gut of some individuals.
Two tablets of EQUELLE should be taken twice daily with a glass of water.
EQUELLE should be taken as long as menopause symptoms like hot flashes and muscle aches persist.
Yes, EQUELLE can be broken or crushed and taken in liquid or food.
Safety & Effectiveness
EQUELLE is safe to take with other foods, supplements, and over-the-counter or prescription medications and will not negatively interact with them. However, EQUELLE should not be taken if you have a soy allergy or sensitivity. If you are pregnant, nursing, taking any medications and/or hormone therapy (HT), you should consult your healthcare professional before taking this product.
In clinical trials, women saw results in as few as 4 weeks, with optimal results in 8 to 12 weeks.
Yes, in two double-blind, randomized controlled trials, S-equol significantly improved hot flash frequency compared to placebo. Read our studies here.. In addition, EQUELLE and its active ingredient S-equol have gone through decades of research, development, and multiple clinical studies to determine the safety of the ingredient.
There are no known common side effects of Equelle. In general, taking botanicals or plant-based supplements may result in possible gastrointestinal upset. If you are experiencing any adverse effects, we recommend discontinuing product use and consulting your physician or healthcare professional.
We aim to make it easy to stay on top of your menopause symptoms. So you never miss a dose, each month we will send you a 30-day supply. We will bill your payment method on file.
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Click the "Account" button located in the top navigation and log into your account. Click on "Billing Information" on the left to see your current billing and shipping information. To change the payment method, simply click "Edit."
Click the "Account" button located in the top navigation and log into your account. Click on "Billing Information" on the left to see your current billing and shipping information. To update shipping or billing addresses, simply click "Edit" next to the desired address.
Click the "Account" button located in the top navigation and log into your account. There you will be able to view your order status and history under "Purchase History" on the left side navigation.
Click the "Account" button located in the top navigation and log into your account. Click on "Delivery Schedule" on the left to see all upcoming deliveries for your subscriptions. To skip a delivery, you can click "Skip" to the right of each one.
Click the "Account" button located in the top navigation and log into your account. Next, click the "Subscriptions" tab on the left-hand side. Next to your subscription is a "Cancel" button to cancel future deliveries.
Shipping & Returns
EQUELLE shipping is always free inside the contiguous US
No, we do not ship internationally at this time.
After placing your order, allow 2–3 days for your order to ship.
We want you to be happy with EQUELLE. We offer a 60-day, money-back guarantee on your first shipment. Simply give us a call at 1-866-EQUELLE, and we will take care of you.