Frequently Asked Questions
What is Equelle?
Hormone-free Equelle, a non-prescription dietary supplement with naturally-derived S-equol, provides menopause symptom relief by helping to reduce the frequency of hot flashes, supporting sleep quality, reducing vaginal irritation, and alleviating mood swings.
How does Equelle work?
Hormone-free Equelle, a non-prescription dietary supplement with naturally derived S-equol, provides menopause symptom relief by helping to reduce the frequency of hot flashes, supporting sleep quality, reducing vaginal irritation, soreness and itching, and alleviating mood swings. S-equol works by mimicking some of the actions of estrogen by preferentially binding to estrogen receptor beta—helping to alleviate hot flash frequency and other symptoms associated with depleting estrogen levels during menopause.
What menopause symptoms does Equelle help with?
Equelle has been clinically validated to alleviate menopause symptoms, such as reducing the frequency of hot flashes, supporting sleep quality, alleviating mood swings, and reducing bothersome vaginal symptoms such as irritation, soreness and itching. In clinical studies, participants taking Equelle experienced reduced hot flash frequency starting as early as week 4, with about 5 fewer hot flashes per day at week 8 compared to baseline. After 12 weeks of taking Equelle participants slept 50 minutes more on an average per night vs. 16 minutes more with placebo.
Is Equelle right for me?
If you're experiencing menopause symptoms like hot flashes, sleep disturbances, vaginal discomfort, and more, Equelle is right for you — whether you are in perimenopause, menopause, or postmenopause.
How is Equelle different than other supplements?
Equelle is a supplement that contains a standardized amount of its active ingredient, S-equol, in every tablet. Many other supplements for menopause are herbal supplements. The growing conditions and potency of herbs (such as black cohosh or evening primrose oil) may be varied and inconsistent, which may impact their effectiveness.
Does Equelle increase Estrogen levels?
Taking Equelle does not impact estrogen levels. Although Equelle’s active ingredient, S-equol, mimics some of the same activities of estrogen by preferentially binding to estrogen receptor beta, Equelle is a hormone free dietary supplement and clinical research shows S-equol supplementation reduces the frequency of hot flashes, supports the quality of sleep, reduces bothersome vaginal symptoms like irritation, soreness and itching, and alleviates mood swings.
How is Equelle naturally derived?
The active ingredient in Equelle, S-equol, is derived naturally through a patented process in which soy germ is fermented.
Fermented soy germ is when soy germ undergoes a process with bacteria that allows for production of key compounds. The type of bacteria used in this process is commonly found in diet through foods that undergo fermentation processes such as cheese. It may also be found in the human gut of some individuals.
Do you offer free samples?
Your doctor may be able to provide you with samples of Equelle. However, samples are not available in all areas. If you are unable to receive samples, we do offer a 90-day money-back guarantee so it's risk-free to try!
How quickly can I expect results?
In clinical trials, Equelle provided menopause symptom relief as early as week 4, with optimal results in 8-12 weeks. Participants receiving Equelle experienced about 5 fewer hot flashes per day at week 8 compared to baseline. After 12 weeks of taking Equelle participants slept 50 minutes more on an average per night vs. 16 minutes more with placebo. After 12 weeks, 92% of participants in an online survey reported they were satisfied with Equelle.
Is Equelle safe to take? Are there any side effects?
Equelle and its active ingredient, S-equol, the active ingredient in Equelle has undergone decades of clinical research and development. It has been shown to be safe and is not associated with changes in sex or thyroid hormones, negative effects on endometrial health or breast cancer. In general, taking botanicals or plant-based supplements may result in possible gastrointestinal upset. If you are experiencing any adverse effects, we recommend discontinuing product use and consulting your physician or healthcare professional.
Does Equelle have any efficacy studies?
Yes, three double-blind, randomized clinical trials were conducted. The results support relief from the common symptoms associated with menopause including reducing frequency of hot flashes and vaginal irritation, alleviating mood swings, and supporting quality of sleep. Read our studies here. In addition, Equelle and its active ingredient S-equol have gone through decades of research, development, and multiple clinical studies to determine the safety of the ingredient.
Is Equelle regulated by the FDA?
Equelle is a dietary supplement regulated by the FDA and we adhere to FDA regulations that require us to follow Current Good Manufacturing Practices (CGMP). The active ingredient in Equelle (S-equol) is also regarded as Generally Recognized as Safe for use in dietary supplements.
Should I avoid any foods, supplements, or medications while on Equelle?
Equelle is safe to take with other foods, supplements, and over-the-counter or prescription medications and will not negatively interact with them. However, Equelle should not be taken if you have a soy allergy or sensitivity. If you are pregnant, nursing, taking any medications and/or hormone therapy (HT), you should consult your healthcare professional before taking this product.
Can I take Equelle if I have had a hysterectomy?
If you are experiencing menopause symptoms due to entering the menopausal transition either naturally or through induced menopause, consider Equelle to alleviate some of these menopause symptoms like frequency of hot flashes, mood swings, vaginal irritation, and to support sleep quality.
Can I take Equelle if I have/had breast cancer?
We always recommend consulting with your healthcare professional to ensure you are making the best decision for your body and needs as this is a deeply personal issue. However, Equelle has been clinically studied and shown to be safe. In fact, a report for the American Institute for Cancer Research notes that a moderate amount of soy (1 to 2 servings a day) is considered safe for survivors and may even be beneficial. Only trace amounts of soy compounds remain in the final Equelle product.
How do I take Equelle?
To achieve full effects during the day and night, two tablets of Equelle should be taken in the morning, and two tablets at night with a glass of water. This will maintain sufficient levels of S-equol in your body to help you with your symptoms throughout the day— morning and night.
How long should I take Equelle?
Menopause symptoms are caused by declining estrogen and you can experience these symptoms for several years, until the body adjusts to those declining levels. Equelle can help relieve these symptoms during this time. Equelle should be taken as long as menopause symptoms persist. If you feel like your symptoms have subsided, you can try to stop taking Equelle and see if your symptoms return. Equelle has been extensively studied and there are no safety issues with taking Equelle for a long period of time.
Can I break or crush Equelle if I can’t swallow it whole?
Yes, Equelle can be broken or crushed and taken in liquid or food.
What are the ingredients in Equelle?
The ingredients in Equelle are: Fermented Soy Germ (S-equol source), Cellulose Gel, Calcium Phosphate, Stearic Acid, Sorbitol, Silicon Dioxide, Sodium Silicate, Croscarmellose Sodium, Organic Coating (Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum).
The active ingredient in Equelle is S-equol, a naturally derived compound ofthe soy isoflavone daidzein that is produced through the fermentation of soy germ. The S-equol used in Equelle is developed using a patented fermentation process that simulates the specific gut conditions needed for certain bacteria to produce S-equol. This process starts by extracting a small amount of soy germ from the bean, which is then added to the fermentation conditions and produces a stabilized and concentrated form of S-equol.
Although daidzein can be consumed in dietary soy products, not everyone who consumes soy foods can produce S-equol. Individuals who can metabolize daidzein into S-equol may experience menopausal symptom relief, as S-equol is structurally similar to estrogen and mimics some, but not all, estrogenic activities.
Is the active ingredient in Equelle also found in foods?
The active ingredient in Equelle is S-equol. Trace amounts of S-equol are found in animal-based foods (i.e. dairy and egg products) due to the fact it’s produced by gut bacteria in animals. Richer food sources of S-equol include popular and traditional fermented tofu products in Taiwan known as chou-doufu. S-equol has also been added to some food bars in the US.
How much soy does Equelle contain?
During our fermentation process, only small trace amounts of soy compounds remain in the final Equelle product. These amounts are significantly less than those present in a single serving of most common soy foods (i.e. 1 oz of soybeans / 3 oz of tofu).
Does Equelle contain phytoestrogens?
Yes. Equelle's active ingredient, S-equol, is derived from soy germ, which is rich in soy isoflavones. Soy isoflavones share a similar structure to human estrogen, which classifies them a phytoestrogen or plant-based estrogen.
How does your auto-delivery program work?
We aim to make it easy to stay on top of your menopause symptoms. So you never miss a dose, each month we will send you a monthly supply, and bill your payment method on file.
I'm having trouble accessing my subscription account. What now?
We’re so sorry to hear that you are having trouble with your account. Simply email us at firstname.lastname@example.org and we will take care of you!
How do I change/update my payment method on my account?
First login to your account here. Then, select “Manage Subscriptions” and "Billing Information" on the left side menu. Here you will see your current billing and shipping information. To change the payment method, simply click "Update Card”. Once you’re all done, don’t forget to hit “Update Card” once again to save any changes.
How do I change/update my shipping or billing address on my account?
Login to your account here. Then, select “Manage Subscriptions” and "Subscriptions" on the left side menu. Here you will see your current subscription and your shipping address listed just above. To update your shipping or billing addresses, simply click "Edit" next to your address. Here you can update either address. Once you’re all done, don’t forget to hit “Save” to update your changes.
How do I view my order history?
Login to your account here. Then, select “Manage Subscriptions”. You will then be able to view your order history under "Purchase History" on the left side navigation.
How do I change my next delivery date? Or skip an order?
To change your next delivery date, click the “Account” button located in the top navigation bar and log into your account. Click on “Manage Subscription”. Then select “Cancel” to the right of your next charge date. Don’t worry, you’re not actually going to cancel. Now click on “Skip Next Delivery”. You will then be given the option to select the number of days you would like to delay your next delivery. To skip an order, simply click on “Delivery Schedule” on the left-hand side menu. Then click "Skip" to the right of each delivery date you would like to skip.
How do I cancel my future shipments?
Login to your account here. Then, select “Manage Subscriptions”. Next, click the "Subscriptions" tab on the left side menu. Next to your subscription is a "Cancel" button to cancel future deliveries.
I do not want to be on a subscription plan. Can I order 1 bottle at a time? Absolutely! In addition to our subscription plan, we also offer a one-time purchase option.
Are shipping fees included?
Yes, in the United States, shipping is always free!
Do you ship internationally?
No, we do not ship internationally at this time.
When will my order arrive?
It takes 2-3 days to process an order plus additional days to ship. Please allow 5-7 business days for your Equelle to arrive. You will receive an email upon order processing and another email once the product has been shipped.
Can I return Equelle if I am unhappy with it?
We want you to be happy with Equelle. We offer a 90-day, money-back guarantee. Simply give us a call at 1-866-Equelle, and we will take care of you.
Can I purchase Equelle in any stores?
Equelle is currently offered online through our website and is not available in stores at this time.