1. Tempfer CB, Froese G, Heinze G, Bentz EK, Hefler LA, Huber JC. Side effects of phytoestrogens: a meta-analysis of randomized trials. Am J Med. 2009;122(10):939-46.e9.
2. Maskarinec G, Verheus M, Steinberg FM, et al. Various doses of soy isoflavones do not modify mammographic density in postmenopausal women. J Nutr. 2009;139(5):981-986.
3. Tousen Y, Ezaki J, Fujii Y, Ueno T, Nishimuta M, lshimi Y. Natural S-equol decreases bone resorption in postmenopausal, non-equal-producing Japanese women: a pilot randomized, placebo-controlled trial. Menopause. 2011;18(5):563-574.
4. Data on File. Global Data 2015; Pharmavite LLC.
What is EQUELLE?
Hormone-free‡ EQUELLE, a non-prescription dietary supplement with naturally-derived S-equol,* provides menopause symptom relief by helping to reduce the frequency of hot flashes, supporting sleep quality, reducing vaginal irritation§, and alleviating mood swings.†
How does EQUELLE work?
Hormone-free‡ EQUELLE, a non-prescription dietary supplement with naturally derived S-equol,* provides menopause symptom relief by helping to reduce the frequency of hot flashes, supporting sleep quality, reducing vaginal irritation, soreness and itching§, and alleviating mood swings.† S-equol works by mimicking some of the actions of estrogen by preferentially binding to estrogen receptor beta—helping to alleviate hot flash frequency and other symptoms associated with depleting estrogen levels during menopause.†
What menopause symptoms does EQUELLE help with?
EQUELLE has been clinically validated to alleviate menopause symptoms, such as reducing the frequency of hot flashes, supporting sleep quality, alleviating mood swings, and reducing bothersome vaginal symptoms such as irritation, soreness and itching§. In clinical studies, participants taking EQUELLE experienced reduced hot flash frequency starting as early as week 4, with about 5 fewer hot flashes per day at week 8 compared to baseline.†¶ After 12 weeks of taking EQUELLE participants slept 50 minutes more on an average per night vs. 16 minutes more with placebo.†
How is EQUELLE different than other supplements?
EQUELLE is a supplement that contains a standardized amount of its active ingredient, S-equol, in every tablet. Many other supplements for menopause are herbal supplements. The growing conditions and potency of herbs (such as black cohosh or evening primrose oil) may be varied and inconsistent, which may impact their effectiveness.
Does EQUELLE increase Estrogen levels?
Taking EQUELLE does not impact estrogen levels. Although EQUELLE’s active ingredient, S-equol, mimics some of the same activities of estrogen by preferentially binding to estrogen receptor beta, EQUELLE is a hormone free‡ dietary supplement and clinical research shows S-equol supplementation reduces the frequency of hot flashes, supports the quality of sleep, reduces bothersome vaginal symptoms like irritation, soreness and itching§, and alleviates mood swings.†
How is EQUELLE naturally derived?
The active ingredient in EQUELLE, S-equol*, is derived naturally through a patented process in which soy germ is fermented.
Fermented soy germ is when soy germ undergoes a process with bacteria that allows for production of key compounds. The type of bacteria used in this process is commonly found in diet through foods that undergo fermentation processes such as cheese. It may also be found in the human gut of some individuals.
Do you offer free samples?
Your doctor may be able to provide you with samples of EQUELLE. However, samples are not available in all areas. If you are unable to receive samples, we do offer a 60-day money-back guarantee so it's risk-free to try!