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The safe, hormone-free menopause symptom relief that women want.†*

Equelle's multi-symptom relief supplement is backed by decades of research that you & your patients can trust.1-3

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A dietary supplement for multi-symptom menopause relief.†

  • Fewer Hot
    Flashes
  • More
    Sleep
  • Relieves MuscleAches
  • Supports
    Healthy Bones

Trust & Safety

Backed by decades of research.1-3

  • No modification

    to breast density

  • No changes

    in sex or thyroid hormone concentrations

  • No negative effects

    to endometrial health identified
“I confidently recommend Equelle to my patients seeking relief from menopausal symptoms. Its clinically studied ingredient offers a natural solution that many women find incredibly beneficial.”
Dr. James A. Simon
MD, CCD, MSCP, IF, FACOG
Equelle Medical Partner
“I’ve been recommending Equelle to my patients for years. It improves sleep, with fewer hot flashes...”
Nurse Barb Dehn
Women’s Health Nurse Practitioner
Certified Menopause Practitioner
Equelle Medical Partner
"Equelle is safe and effective for addressing a wide range of menopausal symptoms, whether you’re still getting your period or haven’t had it in 20 years."
Dr. Kellogg-Spadt
PhD, CRNP
Equelle Medical Partner
"I am committed to conducting scientific research that helps women full stop! Navigating and managing symptoms associated with estrogen decline is hard; we believe that women need multiple tools in the tool box to help them on their menopause journey."
Dr. Susan Mitmesser
PhD Nutrition Biochemistry
Chief Science Officer, Equelle
"Each woman's menopause journey is so unique and I am grateful to provide support for these women as they navigate this important life change."
Heather Ott
Registered Dietitian Nutritionist (RDN)
Senior Equelle Health & Science Educator

What is in Equelle?

Powered by S-equol.

Beyond a soy isoflavone.

Harvested from soy germ, S-equol is a targeted isoflavone metabolite with decades of safety and efficacy research behind it.

S-equol is naturally produced by
the human gut when daidzein, a
soy isoflavone, is metabolized

Some women naturally
produce S-equol through soy
consumption4

Equelle uses S-equol to provide symptom relief during menopause

Mechanism of Action

S-equol has unique binding properties.5

S-equol is structurally similar to estrogen allowing it to mimic some estrogenic effects for targeted relief.

S-equol preferentially binds to ER-β. Unlike ER-α, ER-β is rarely expressed in:

  • Mammary glands
  • Ovarian theca cells
  • Uterus

Medical FAQs

  • Each tablet of Equelle contains 5mg of S-Equol and 120mg of Calcium.

  • It is recommended to take 10mg of Equelle daily, with or without food

  • No! Equelle is non-prescription, hormone-free* support for multi symptom menopause relief.

  • In clinical trials, Equelle provided menopause symptom relief as early as 1 month, with optimal results in 2-3 months.6-9

  • Equelle is available on subscription for $40/month or $50/month for a one-time purchase. Let us know if you would like samples and/or coupons for your patients at healthcare@equelle.com.

  • Equelle is exclusively available through our website. Please encourage them to visit www.equelle.com to learn more and buy Equelle today!

Ready to get started?

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coupons.

Please fill out the form below to request Equelle welcome materials and/or receive the latest information on Equelle.

Have a question? We’re happy to help.

You can email us at healthcare@equelle.com.