All-in-one natural menopause relief.

Equelle is the only supplement with S-equol, proven to address the root cause of menopause symptoms by naturally mimicking estrogen.

SHOP EQUELLE

All-in-one natural menopause relief.

Equelle is the only supplement with S-equol, proven to address the root cause of menopause symptoms by naturally mimicking estrogen.

SHOP EQUELLE
Plant-based and Powerful

Plant-based and Powerful

Equelle is powered by S-equol — a plant-based ingredient that is clinically proven to relieve a range of menopause symptoms 1

Fewer hot flashes

Fewer hot flashes

More sleep

More sleep

Improves mood

Improves mood

Reduces vaginal symptoms

Reduces vaginal symptoms

Alleviates muscle aches

Alleviates muscle aches

How does Equelle work?

How does Equelle work?

Traditional hormone replacement therapy replaces the estrogen that your body stops making during menopause. These hormones bind to estrogen receptors all over the body, including breast, ovarian, and uterine tissues.

Equelle's plant-based ingredient, S-equol, binds only to some estrogen receptors, relieving menopause symptoms while not effecting breast, ovarian, or uterine tissues.

Read more here.

20 years of clinical research for proven safety

Equelle's active ingredient, S-equol, is a plant-based compound clinically researched for decades, recognized as safe by the FDA, and proven safe with:

No association with breast cancer or other cancers
No changes in sex or thyroid hormones
No negative effects on endometrial health

Results with the data to back them up

In randomized, placebo-controlled clinical trials, women taking Equelle experienced 1 :

+50

more minutes of sleep 5

-5

fewer hot flashes per day 3

92%

satisfaction

Ready to get relief from your menopause symptoms?

Brought to you by America's #1 Pharmacist Recommended Vitamin & Supplement Brand

Equelle is trusted by over 300,000 women and recommended by thousands of doctors in Japan. After 20 years of research, Equelle is being brought to the United States exclusively by the makers of Nature Made, the #1 Pharmacist Recommended Vitamin & Supplement Brand 2   in America.

Our refund policy

We know it’s important to try Equelle to make sure it works for you. Some women see relief in as early as 1 month, with optimal results in 2-3 months.

That's why we have a 90 day money-back guarantee. If Equelle doesn’t work for you, we’ll make it easy and refund you in full. Our team is here to help!

Real reviews from real women

This area allows women like you to express their own opinions and comments about Equelle. We stay out of it! These reviews are unfiltered and uncurated.

For Health Care Practitioners

Find out how Equelle can help your patients.

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