Real Relief from Menopause Symptoms

From the #1 Pharmacist Recommended Brand

Safe to use

S-equol, the active ingredient in EQUELLE, mimics estrogen but is a plant-based, naturally-derived compound that is produced by some women in the gut in small amounts. S-equol has been extensively studied and proven safe1 with:
  • NO association with breast cancer2
  • NO changes in sex or thyroid hormones3
  • NO negative effects on endometrial health4
In general, taking botanicals or plant-based supplements may result in possible gastrointestinal upset. FAQs about taking EQUELLE →


EQUELLE has been clinically validated to alleviate menopause symptoms. In a clinical study, participants taking EQUELLE experienced fewer hot flashes starting as early as week 4, with about 5 fewer hot flashes per day at week 8.

After 12 weeks of taking EQUELLE participants slept 50 minutes more on average per night vs. 16 minutes more with placebo.

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Tried & trusted by real women

After a 12-week trial, 92% of women said they were satisfied with their results from EQUELLE.

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100% Satisfaction Guaranteed

EQUELLE comes with a 60-day money back guarantee, because our commitment to science, substance, and quality is just as strong as our commitment to you.

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Over 200,000 women already trust in EQUELLE.

"I took it in the morning and I took it at night, and it was easy to remember, and it really helped."

"After 6 weeks of taking EQUELLE, I really felt like a much better version of myself."

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1. Tempter CB, Froese G, Heinze G, Bentz EK, Hefler LA, Huber JC. Side effects of phytoestrogens: a meta-analysis of randomized trials. Am J Med. 2009;122(10}:939-46.e9.
2. Maskarinec G, Verheus M, Steinberg FM, et al. Various doses of soy isoflavones do not modify mammographic density in postmenopausal women. J Nutr. 09;139(5):981-986.
3. Tousen Y, Ezaki J, Fujii Y, Ueno T, Nishimuta M, lshimi Y. Natural S-equol decreases bone resorption in postmenopausal, non-equal-producing Japanese women: a pilot randomized, placebo-controlled trial. Menopause. 2011;18(5}:563-574.
4. Data on File. Global Data 2015; Pharmavite LLC.