more minutes of sleep per night 2


fewer hot flashes per day 1


vaginal symptoms 2


overall mood 2

How long will it take to feel the effects of Equelle?

In clinical trials, Equelle provided menopause symptom relief as early as month 1, with optimal results in 2-3 months. That's why we offer a 90 day money-back guarantee. Because S-equol works by safely mimicking estrogen in the body, it takes time to reach optimum results. The results on Equelle have been separately validated in 3 randomized, placebo-controlled clinical trials. 3-5

Your journey might be different than others, but this is a look at what other women experienced in clinical trials:

  • The journey to symptom relief begins.

  • You may be able to notice fewer hot flashes and improved quality of sleep.
  • Your symptoms may continue to improve. If you’re not feeling the full effect, hang in there!
  • You may be enjoying an additional 50 minutes of sleep per night, improved mood, improved vaginal symptoms, and up to 58% fewer hot flashes. 2,4†#⁋||
  • Consistency is the key to success! Remember fluctuations in symptoms is normal and can be triggered by changes in lifestyle. Stick with it to maintain optimal results!

See the Clinical Research for yourself

As published in the Journal of Women's Health

A Natural S-equol Supplement Alleviates Hot Flushes and Other Menopausal Symptoms in Equol Nonproducing Postmenopausal Women

As published in menopause, the journal of the North American Menopause Society

New Equol Supplement for Relieving Menopausal Symptoms: Randomized, Placebo-controlled Trial of Women

As published in Journal of Women's Health

A Pilot Study on the Effects of S-equol Compared to Soy Isoflavones on Menopausal Hot Flash Frequency

A collection of publications on the clinical research and development of s-equol

A collection of 16 research reports and clinical trials on S-equol’s development and menopause symptom relief benefits from 2007 to 2014

S-equol is backed by decades of safety & efficacy research. 3,6-7

Ready to get relief from your menopause symptoms?