CLINICAL RESULTS

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PEER-REVIEWED RESEARCH

We collaborate with experts and researchers in the scientific community to publish
research in peer-reviewed scientific journals.
As published in
Journal of Women's Health

A Natural S-equol Supplement Alleviates Hot Flushes and Other Menopausal Symptoms in Equol Nonproducing Postmenopausal Women. Read full article.

As published in
Journal of Women's Health

A Pilot Study on the Effects of S-equol Compared to Soy Isoflavones on Menopausal Hot Flash Frequency. Read the abstract.

A collection of publications
Clinical Research and Development of S-equol

A collection of research reports and clinical trials on S-equol’s development and menopause symptom relief benefits from 2007 to 2014. Read more.

IN CLINICAL TRIALS

Real women reported

  • Fewer hot flashes per day1,4†
  • Relief from muscle aches1,4†
  • Supported sleep quality2||⁋†

DECADES OF RESEARCH AND DEVELOPMENT

First demonstration that S-equol can be converted from soy by gut mircoflora.
Setchell KD, et al. Am J Clin Nutr. 1984;40:569-78.

Soy flour consumption linked to menopause symptom reduction
Murkies AL, et al. Maturitas. 1995;21(3): 189-95.

Higher S-equol production linked to reduced menopause symptoms
Uchiyama S, et al. J Jpn Menopause Soc. 2007;15:28-37.

Clinically studied in randomized controlled trials and published. 1,3,4

Equelle launches in Japan

Equelle launches in U.S.

Clinical trial assessing multiple menopausal symptoms including sleep in a U.S. population2

Clinical results presented at North American Menopause Society Annual Meeting showing the first efficacy data on sleep7||

Meet our panel of healthcare practitioners

“I’ve been recommending Equelle to my patients for years. It improves sleep, with fewer hot flashes ...”
Nurse Barb Dehn
Women’s Health Nurse Practitioner
Certified Menopause Practitioner
Equelle Medical Partner
“I confidently recommend Equelle to my patients seeking relief from menopausal symptoms. Its clinically studied ingredient offers a solution that many women find incredibly beneficial.”
Dr. James A. Simon
MD, CCD, MSCP, IF, FACOG
Equelle Medical Partner
"Equelle is one of the favorite tools in my menopause toolbox. Patients love that it contains a plant sourced ingredient, S-equol, and I love that it is well studied, safe and effective"
Dr. Maria Sophocles
MD, FACOG, MSCP, IF
Menopause and Sexual Function Expert Author
Ted speaker, Equelle Medical Partner
"Equelle is safe and effective for addressing a wide range of menopausal symptoms, whether you’re still getting your period or haven’t had it in 20 years."
Dr. Kellogg-Spadt
PhD, CRNP
Equelle Medical Partner
"Each woman's menopause journey is so unique and I am grateful to provide support for these women as they navigate this important life change."
Heather Ott
Registered Dietitian Nutritionist (RDN)
Senior Equelle Health & Science Educator
"I am committed to conducting scientific research that helps women full stop! Navigating and managing symptoms associated with estrogen decline is hard; we believe that women need multiple tools in the tool box to help them on their menopause journey."
Dr. Susan Mitmesser
PhD Nutrition Biochemistry
Chief Science Officer, Pharmavite
Pharmavite is parent company to Equelle

Menopause symptom relief in 90 days or less†

We know how important it is to make sure supplements work for you. If Equelle doesn’t work for you, we’ll make it easy and refund you in full with our money back guarantee.
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