Multi-symptom
menopause relief.
Guaranteed.

Equelle is a revolutionary supplement, clinically studied to provide menopause support or your money back.
  • HORMONE-FREE*
  • NO PRESCRIPTION
  • CLINICALLY STUDIED

2 tablets, once daily, for menopause relief in 90 days or less1,2,4†

  • Fewer
    Hot Flashes1,4
  • More
    Sleep2||
  • Relieves
    Muscle Aches1,4
  • Supports
    Healthy Bones3,5

A new level of menopause care

The power of S-equol

Equelle is a game-changing supplement powered by S-equol, a plant-based metabolite that mimics the effects of estrogen to relieve the most bothersome menopausal symptoms.6†
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We are personalized
1:1 support

Because every menopause journey is unique, our commitment extends beyond the bottle to educate and support you every step of the way.

Real results you can trust

In randomized controlled trials women taking Equelle experienced significant improvements in menopausal symptom relief.1,4

Helping thousands of women find lasting relief

"I just started my third month, and WOW! Symptoms are almost completely gone! This is the first product that has actually worked..."
Shannon R., 50-54
Verified Customer
"I am so happy I found Equelle...I am on my third bottle. It gradually started working but I started noticing the symptoms getting lighter around the second bottle"
Leslie H., 55-59
Verified Customer
"I've taken Equelle for years and have been thrilled with the results- minimal hot flashes and better sleep to name a few."
Shawna W., 50-54
Verified Customer
"My experience with Equelle was amazing!... the staff was so helpful and supportive in my journey especially when needing advice. Not disappointed."
Karen S., 55-59
Verified Customer
"I am just about to finish my second bottle and I have noticed so much of a positive change"
Nancy O., 60-64
Verified Customer
"Equelle has THE best customer service ever. I am grateful for the personalized responses I receive when I have questions about my health. Keep it up, Equelle."
Niamh M., 60-64
Verified Customer
"This supplement is a game changer!!!... Equelle gave me my life back. I cannot thank this company enough for all that you do..."
Skylar, 45-49
Verified Customer
"I’m on my 4th month of taking Equelle and I feel more like myself..."
Camille G., 45-49
Verified Customer

S-equol is backed by safety & efficacy research.1-4,6

You deserve a solution that is safe, effective and grounded in science. That’s why we have decades of research led by scientific experts.6

Meet our panel of healthcare practitioners

Nurse Barb Dehn
Women's Health Nurse Practitioner
Certified Menopause Practitioner
Equelle Medical Partner

“I’ve been recommending Equelle to my patients for years. It improves sleep, with fewer hot flashes...”

Nurse Barb Dehn Women's Health Nurse PractitionerCertified Menopause PractitionerEquelle Medical Partner

Dr. James A. Simon
MD, CCD, MSCP, IF, FACOG
Equelle Medical Partner

“I confidently recommend Equelle to my patients seeking relief from menopausal symptoms. Its clinically studied ingredient offers a solution that many women find incredibly beneficial.”

Dr. James A. Simon MD, CCD, MSCP, IF, FACOGEquelle Medical Partner

Dr. Kellogg-Spadt
PhD, CRNP
Equelle Medical Partner

"Equelle is safe and effective for addressing a wide range of menopausal symptoms, whether you’re still getting your period or haven’t had it in 20 years."

Dr. Kellogg-Spadt PhD, CRNPEquelle Medical Partner

Heather Ott
Registered Dietitian Nutritionist (RDN)
Senior Equelle Health & Science Educator

"Each woman's menopause journey is so unique and I am grateful to provide support for these women as they navigate this important life change."

Heather Ott Registered Dietitian Nutritionist (RDN)Senior Equelle Health & Science Educator

Dr. Susan Mitmesser
PhD Nutrition Biochemistry
Chief Science Officer, Equelle

"I am committed to conducting scientific research that helps women full stop! Navigating and managing symptoms associated with estrogen decline is hard; we believe that women need multiple tools in the tool box to help them on their menopause journey."

Dr. Susan Mitmesser PhD Nutrition BiochemistryChief Science Officer, Equelle
Nurse Barb Dehn Women's Health Nurse PractitionerCertified Menopause PractitionerEquelle Medical Partner
Dr. James A. Simon MD, CCD, MSCP, IF, FACOGEquelle Medical Partner
Dr. Kellogg-Spadt PhD, CRNPEquelle Medical Partner
Heather Ott Registered Dietitian Nutritionist (RDN)Senior Equelle Health & Science Educator
Dr. Susan Mitmesser PhD Nutrition BiochemistryChief Science Officer, Equelle

AS FEATURED IN

Our promise

We’re committed to helping you find relief – every step of the way. If Equelle doesn’t work for you, we’ll make it easy and refund you in full with our 90 day money-back guarantee.