Multi-symptom menopause
relief in 90 days or less.†
See results in as little as 4 weeks and continue taking for 90 days to see optimal results.¹⁻²,⁴
Multi-symptom menopause
relief in 90 days or less.†
See results in as little as 4 weeks and continue taking for 90 days to see optimal results.¹⁻²,⁴
Results from women just like you
86% Satisfaction Rate‡
8/10 Women Would
Recommend to a Friend‡
1600+ 5-star Reviews
1500+ Healthcare
Practitioners Trust
Rated 4.2/5 from 2,560+ Reviews
Powered by S-equol, a plant-based ingredient derived from soy that 1-6†:
Reduces hot flashes
Improves sleep quality||⁋
Reduces muscle aches
Helps support bone health
Is hormone-free* and backed by safety & efficacy research
Multi-symptom menopause relief for better quality of life
Is easy to use as one supplement that targets multiple symptoms of menopause
Two Tablets Daily
Hormone-Free*
90 Day Money-Back Guarantee
FREE SHIPPING
In stock, ready to ship
We recommend 90 days of consistent use for best results
What is S-equol?
S-equol is the key ingredient in Equelle. It is a plant-based compound produced through the fermentation of soy germ and is naturally produced by some women in the gut in small amounts after consuming soy.
Is Equelle safe to take? Are there any side effects?
Equelle’s key ingredient, S-equol, has undergone decades of scientific research. It has been studied to be safe in clinical trials.
In general, taking botanicals or other supplements may result in possible gastrointestinal upset. We recommend taking Equelle with food if you experience stomach sensitivity with supplements.
If you are experiencing any other adverse effects, we recommend discontinuing product use and consulting your physician or healthcare professional. Also, please reach out to us at hello@equelle.com.
How much soy does Equelle contain? Can I take Equelle if I have a soy allergy?
Only a small amount of soy is in Equelle. This amount is less than the amount in a single serving of common soy foods.
Since Equelle contains soy, Equelle should not be taken if you have a soy allergy or sensitivity.
What are the ingredients?
Key Ingredient: S-equol
Inactive Ingredients: Dicalcium Phosphate, Fermented Soy Germ, Silicon Dioxide, Croscarmellose Sodium, Magnesium Stearate, Coating (Hypromellose, Glycerin, Hydroxypropyl Cellulose), Microcrystalline Cellulose.
Contains Soy
Should I avoid any supplements or medications when taking Equelle?
Equelle’s formulation contains calcium, which is recommended to be taken separately from both iron and thyroid medications for proper absorption. For specific guidance, we recommend the following: Iron Supplements and/or Multivitamins Containing Iron: take 1-2 hours apart from Equelle. Thyroid Medication: take Equelle 4 hours apart from your thyroid medication.
We always recommend you discuss any supplement use with your doctor.
S-equol + Estrogen Decline
Key ingredient works by mimicking estrogen.⁶
Take 2 tablets daily for
multi-symptom menopause relief†
See results in as little as 4 weeks and continue taking for 90 days to see optimal results.¹⁻²,⁴
Formulated with plant-based S-equol that is hormone-free*
S-equol + Estrogen Decline
Key ingredient formulated to mimic estrogen.
Take 2 tablets daily
for multi-symptom menopause relief†
See results in as little as 4 weeks and continue taking for 90 days to see optimal results.¹⁻²,⁴
Formulated with plant-based
S-equol that is hormone-free*
About Equelle
Equelle is a hormone-free* supplement clinically studied to provide menopause symptom relief.†
Equelle, powered by plant-based S-equol¹⁻⁶†:
Reduces hot flashes
Improves sleep quality||⁋
Reduces muscle aches
Helps support bone health
Is hormone-free* and backed by safety & efficacy research
Is easy to use as one supplement that targets multiple symptoms of menopause

Get your body back
What can change in 90 days?
Day 30
Signs of menopause symptom relief
You may be able to notice fewer hot flashes and supported sleep. 1,2,4†||⁋
Day 60
Building momentum
Your symptoms may continue to improve. If you're not feeling the full effect, hang in there!
Day 90
Feel like yourself again
You may be enjoying relief from hot flashes, muscle aches, and poor sleep quality.1,2,4†||⁋
Month 4 & beyond
Consistency is key
Remember fluctuations in symptoms are normal and can be triggered by changes in lifestyle. Stick with it to maintain optimal results!