Get real relief from your menopause symptoms.

Equelle is a revolutionary supplement that is clinically studied to provide relief from symptoms of estrogen decline.†
Get relief now
  • CLINICALLY STUDIED
  • HORMONE-FREE*
  • NO PRESCRIPTION

Get multi-symptom menopause relief for a better quality of life1,2,4

Equelle is clinically studied to provide multi-symptom menopause relief.
Get relief from hot flashes and more. †
Get relief now

2 tablets, once daily, for menopause relief in 90 days or less1,2,4†

  • Fewer
    Hot Flashes1,4
  • More
    Sleep2||
  • Relieves
    Muscle Aches1,4
  • Supports
    Healthy Bones3,5

A new level of menopause care

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Equelle bottle and tablets

The power of S-equol

Equelle is a game-changing supplement powered by S-equol, a plant-based metabolite that mimics the effects of estrogen to relieve the most bothersome menopausal symptoms.6†
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Two women holding Equelle bottles

We are personalized 1:1 support

Because every menopause journey is unique, our commitment extends beyond the bottle to educate and support you every step of the way.
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Equelle tablets in hand

Real results you can trust

In randomized, placebo-controlled clinical trials, women taking Equelle experienced significant improvements in menopausal symptom relief.1,4
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Helping thousands of women find lasting relief

"My experience with Equelle was amazing!... the staff was so helpful and supportive in my journey especially when needing advice. Not disappointed."
Karen S., 55-59
Verified Customer
"I've taken Equelle for years and have been thrilled with the results- minimal hot flashes and better sleep to name a few."
Shawna W., 50-54
Verified Customer
"I am just about to finish my second bottle and I have noticed so much of a positive change"
Nancy O., 60-64
Verified Customer
"Equelle has THE best customer service ever. I am grateful for the personalized responses I receive when I have questions about my health. Keep it up, Equelle."
Niamh M., 60-64
Verified Customer
"I love it. It really does what they say it does."
Hannah J., 50-54
Verified Customer
"I’m on my 4th month of taking Equelle and I feel more like myself..."
Camille G., 45-49
Verified Customer
"I am so happy I found Equelle...I am on my third bottle. It gradually started working but I started noticing the symptoms getting lighter around the second bottle"
Leslie H., 55-59
Verified Customer
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S-equol is backed by safety & efficacy research.1-4,6

You deserve a solution that is safe, effective and grounded in science. That’s why we have decades of research led by scientific experts. 6

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Meet our panel of healthcare practitioners

“I’ve been recommending Equelle to my patients for years. It improves sleep, with fewer hot flashes...”
Nurse Barb Dehn
Women’s Health Nurse Practitioner
Certified Menopause Practitioner
Equelle Medical Partner
“I confidently recommend Equelle to my patients seeking relief from menopausal symptoms. Its clinically studied ingredient offers a solution that many women find incredibly beneficial.”
Dr. James A. Simon
MD, CCD, MSCP, IF, FACOG
Equelle Medical Partner
"Equelle is safe and effective for addressing a wide range of menopausal symptoms, whether you’re still getting your period or haven’t had it in 20 years."
Dr. Kellogg-Spadt
PhD, CRNP
Equelle Medical Partner
"Each woman's menopause journey is so unique and I am grateful to provide support for these women as they navigate this important life change."
Heather Ott
Registered Dietitian Nutritionist (RDN)
Senior Equelle Health & Science Educator
"I am committed to conducting scientific research that helps women full stop! Navigating and managing symptoms associated with estrogen decline is hard; we believe that women need multiple tools in the tool box to help them on their menopause journey."
Dr. Susan Mitmesser
PhD Nutrition Biochemistry
Chief Science Officer, Equelle

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Our promise

We’re committed to helping you find relief – every step of the way. If Equelle doesn’t work for you, we’ll make it easy and refund you in full with our 90 day money-back guarantee.
Try Equelle today