Natural alternative to estrogen.

Equelle works by naturally mimicking estrogen, for safe menopause symptom relief.

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Natural alternative to estrogen.

Equelle works by naturally mimicking estrogen, for safe menopause symptom relief.
Equelle gives you relief

Equelle gives you relief

Equelle is powered by S-equol — a plant-based ingredient researched for over 20 years that relieves a range of menopause symptoms:

Fewer hot flashes

Fewer hot flashes

More sleep

More sleep

Improved mood

Improved mood

Reduced vaginal symptoms

Reduced vaginal symptoms

How does Equelle do it all?

How does Equelle do it all?

By safely and naturally mimicking estrogen.

As estrogen levels decrease, menopause symptoms go up.

S-equol acts like estrogen in your body. As S-equol levels increase, menopause symptoms go down.

A safe alternative to hormone replacement therapy

S-equol is derived from soy using a patented process and has been extensively studied and proven safe with:

No association with breast cancer
No changes in sex or thyroid hormones
No negative effects on endometrial health

Results with the data to back them up

In randomized, placebo-controlled clinical trials, women taking Equelle experienced:

+50

more minutes of sleep 4

-5

fewer hot flashes per day 2

92%

satisfaction

Ready to get relief from your menopause symptoms?

Brought to you by America's #1 pharmacist recommended brand

Equelle is trusted by over 300,000 women and recommended by thousands of doctors in Japan. After 20 years of research, Equelle is being brought to the United States exclusively by the makers of Nature Made, the #1 pharmacist recommended brand in America 1.

Finally, the menopause relief you deserve

Powered by plants

Powered by plants

S-equol is a plant-based compound that can be produced by 20% of women in the gut. As a result, these women experience more mild menopause symptoms. However, they are unable to produce enough S-equol to fully alleviate menopause symptoms and can still benefit from Equelle.

Researched for over 20 years

Researched for over 20 years

Equelle is built on 20 years of research and development and uses a patented production process. In clinical trials, Equelle showed a significant reduction in many of the most bothersome menopause symptoms.

Safe to take & hormone-free

Safe to take & hormone-free

S-equol provides a safe alternative to hormone replacement therapy. Extensive clinical research has validated that S-equol relieves the symptoms of menopause without negative health effects.

Our refund policy

Your health and happiness are our top priority. If Equelle doesn’t work for you, we’ll make it easy and refund you in full with our 90-day money-back guarantee. No questions asked – just reach out to us.