EQUELLE's active ingredient, S-equol, is backed by decades of clinical research and is specially formulated to deliver consistent menopause symptom relief.†
Try EQUELLE today

Naturally Derived

S-equol mimics estrogen, but is a plant-based, naturally derived compound that is also produced by some women in the gut. But it's nearly impossible to produce the amount of S-equol that one daily serving of EQUELLE provides.

Research Backed

EQUELLE is based on over 20 years of research and uses a patented fermentation process which recreates these natural conditions to provide you with a safe and reliable supplement for managing menopause symptoms.

Consistent Relief

While natural remedies like black cohosh or evening primrose oil may vary depending on soil or environment, EQUELLE delivers consistent amounts of S-Equol in every serving to provide consistent menopausal symptom relief.

Clinical studies show EQUELLE works

It may take some time to experience the full relief of EQUELLE. Clinical studies show benefits in as little as 4 weeks and optimal results after 8–12 weeks.

Peace of mind

EQUELLE has been shown to be safe and is not associated with changes in sex or thyroid hormones, negative effects on endometrial health or breast cancer. In general, taking botanicals or plant-based supplements may result in possible gastrointestinal upset.

Don’t settle for anything less than relief

While menopause is technically only one day in a woman’s life, menopause symptoms can last 7–10 years. But frequent hot flashes, sleep difficulties, mood swings, and vaginal discomfort don't have to be your new normal.

Take control of your health with EQUELLE, clinically validated to provide real relief from menopause symptoms. Findings show some experience benefits in as little as 4 weeks.** Experience our naturally derived relief for yourself or get your money back.* It’s that simple.

Real results

Over 200,000 women already trust in EQUELLE every day for over-the-counter menopause relief.

Read reviews →

Taking EQUELLE is easy

No prescription necessary, simply follow the steps below and discover a new kind of menopausal relief.

1. Order EQUELLE

One-time purchase or monthly subscription, the choice is yours.
Free contiguous U.S. shipping.

2. Create a new routine

Take two in the morning and two in the evening to maintain symptom relief throughout the day.

3. Sit back and relax

And enjoy real menopause symptom relief starting in as little as 4 weeks**

Try hormone-free EQUELLE today.

Order now

EQUELLE comes with a 60-day money back guarantee, because our commitment to science, substance, and quality is just as strong as our commitment to you.

Details 🡪